siRNA Modification
Transfect and visualise your siRNA with our modifications
Rely on our long years' expertise in modifying single-stranded RNA.
We offer a selection of modifications to accomplish duplex stability, increase nuclease resistance or to track transfection efficiency.
- Guaranteed purity
HPLC purification ensures a purity of >80% - Minimum yields
Minimum yields in nmol for 3 different synthesis scales - Highest quality
Verified by MALDI-TOF MS and CGE analysis
Select from a variety of modifications for your 21mer or 27mer siRNA sense and antisense strands.
|
Fluorescent dyes |
5' |
3' |
|
FAM |
x |
- |
|
Fluorescein |
- |
x |
|
HEX |
x |
- |
|
TET |
x |
- |
|
Cyanine3 |
x |
- |
|
Cyanine5 |
x |
- |
|
Non-fluorescent modifications |
5' |
3' |
|
Amino-Modifier C6/C12 |
x |
- |
|
Amino-Modifier C3/C6/C7 |
- |
x |
|
Biotin |
x |
x |
|
Biotin-TEG |
x |
x |
|
Phosphate (PHOs) |
x |
x |
Specification
What you can expect from our modified siRNAs
Product specifications:
- Guaranteed purity of >80% measured by CGE
- HPLC purification by default
- Minimum yields in nmol
- TAT: 3-4 weeks
- Delivery: ready-to-use duplex, lyophilised in tube format
- Quality control by OD measurement, MALDI-TOF MS and CGE
|
Synthesis scales |
Guaranteed yields |
|
|
0.05µmol |
5nmol |
|
|
0.2µmol |
15nmol |
|
|
1.0µmol |
30nmol |
|
The synthesis scale indicates the initial amount of 3' bases. Purity is based on capillary gel electrophoresis (CGE) analysis of the single strand before the duplex is annealed.
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