Gene Synthesis

25 years ago site directed mutagenesis was invented and everyone tried to introduce mutations in genes: with more or less success and the time it will take to achieve success is indefinite.

Today we are at the next level of science. Any double stranded DNA sequence can be synthesised de novo: effectively and on schedule.

Receive brand-new synthetic genes in just 15WD - and get a head start on your individual project time table. Improve gene expression and remove bad motifs like secondary structures from your DNA fragments.

Make time your best friend - we will find the correct clone for you.

Choose your gene

Depending on the length and complexity of a gene or project we offer different categories of synthetic genes.

Standard genes

Standard genes are defined by the following criteria:

• Moderate GC content (40-65%)
• No extensive repeats (>20bp) or critical hairpin structures
• No extensive homopolymer stretches (>20bp)

Complex genes

If any of the following descriptions below match your request, our service category complex genes would be most suitable for you:

• Consultation included
• Extreme GC content (very high or low)
• Long repeats or secondary structures are part of the gene

Gene Strands

Gene Strands are a cost-efficient alternative for short genes with no complexities:

• Delivery time: 15WD
• GeneStrands lengths: 20 - 99 bp
• Delivered as linear, double-stranded DNA fragments

Application:

One gene - millions of applications

Synthetic genes: the universal key in molecular biology

Expression improvement in heterologous systems

• Codon usage adaptation
• Promoter and enhancer elements

Cloning applications

• Subcloning
• cDNA cloning
• qPCR and PCR standards

Optimisation of constructs

• Introduction/removal of good and bad motifs
• Construction of hybrid genes
• Screening for improved properties of proteins